Before we begin, I want to clarify that both DynamoRIO and Pin are great tools that I use all the time. Dynamic Binary Modification is a very powerful technique in general. However, both implementations have a limitation which can have serious security implications for some uses cases and which, as far as I can tell, is not documented in the user manuals. I got in touch with people involved in both projects and they've explained that they consider it low risk for the typical usage scenario and that fixing it would add performance overhead. This is a perfectly reasonable position, but I think this sort of low risk / high impact issue should be very well and visibly documented.
more here..........https://github.com/lgeek/dynamorio_pin_escape
more here..........https://github.com/lgeek/dynamorio_pin_escape